Human follicle-stimulating hormone(FSH)
- 别名:FSH, follitropin
FSH is a 35.5 kDa glycoprotein heterodimer, consisting of two polypeptide units, alpha and beta. Its structure is similar to those of luteinizing hormone (LH), thyroid-stimulating hormone (TSH), and human chorionic gonadotropin (hCG). The alpha subunits of the glycoproteins LH, FSH, TSH, and hCG are identical and consist of about 96 amino acids, while the beta subunits vary. Both subunits are required for biological activity. FSH has a beta subunit of 111 amino acids (FSH β), which confers its specific biologic action, and is responsible for interaction with the follicle-stimulating hormone receptor. The sugar portion of the hormone is covalently bonded to asparagine, and is composed of N-acetylgalactosamine, mannose, N-acetylglucosamine, galactose, and sialic acid
- 纯度:>90% by SDS-PAGE
- 形态:Supplied in liquid form in 20mM Tris-HCl, 500 mM NaCl, pH 8.0, 50% glycerol
- 保存条件:Aliquot and store at -20 ℃ or -80 ℃. Avoid repeated freeze / thaw cycles
- 应用:Calibrator or standard in ELISA, CLIA and other possible application.
- 活性:Immunological activity can be determined by double antibody sandwich chemiluminescence immunoassay